RN029 | Classification of renal tumors

Case ID: 274

Publication date: 22 Apr, 2026

Consensus grade: MiT Family translocation carcinoma

Show diagnosis by expert panel members

User	Diagnosis	Difficulty	Comment
Pathologist 1	MiT Family translocation carcinoma	Typical
Pathologist 2	MiT Family translocation carcinoma	Not typical	IHC or FISH evidence of translocation is required. If not present, it would be an unclassified RCC.
Pathologist 3	MiT Family translocation carcinoma	Typical
Pathologist 4	MiT Family translocation carcinoma	Typical
Pathologist 5	MiT Family translocation carcinoma	Typical
Pathologist 6	MiT Family translocation carcinoma	Typical
Pathologist 7	MiT Family translocation carcinoma	Not typical	I would support my diagnosis by FISH (Xp11.2)
Pathologist 8	MiT Family translocation carcinoma	Typical
Pathologist 9	MiT Family translocation carcinoma	Typical
Pathologist 10	MiT Family translocation carcinoma	Typical
Pathologist 11	MiT Family translocation carcinoma	Typical
Pathologist 12	MiT Family translocation carcinoma	Typical
Pathologist 13	MiT Family translocation carcinoma	Typical
Pathologist 14	MiT Family translocation carcinoma	Typical
Pathologist 15	MiT Family translocation carcinoma	Typical
Pathologist 16	MiT Family translocation carcinoma	Typical	TFE3?
Pathologist 17	MiT Family translocation carcinoma	Typical

Case description (by case creator):

MiT Family translocation carcinoma
PRCC-TFE3

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