Case ID: 59

Publication date: 22 Dec, 2024

Consensus grade: Clear cell RCC

User Diagnosis Difficulty Comment
Pathologist 1 Clear cell RCC Typical

With focal rhabdoid areas

Pathologist 2 MiT Family translocation carcinoma Not typical
Pathologist 3 Clear cell RCC Not typical
Pathologist 4 Clear cell RCC Typical
Pathologist 5 Clear cell RCC Typical

Grade 4

Pathologist 6 Clear cell RCC Typical
Pathologist 7 Clear cell RCC Typical

High grade with rhabdoid cells

Pathologist 8 Clear cell RCC Not typical

Interesting rhabdoid and giant cell features

Pathologist 9 Clear cell RCC Typical
Pathologist 10 Clear cell RCC Typical
Pathologist 11 Other Typical

I favour atypical epithelioid AML - would perform IHC to confirm this and rule out RCC

Pathologist 12 Clear cell RCC Typical
Pathologist 13 Clear cell RCC Not typical

CCRCC with giant cells

Pathologist 14 Clear cell RCC Typical

rhabdoid aspects

Pathologist 15 Clear cell RCC Not typical
Pathologist 16 Oncocytic RCC post-neuroblastoma Not typical
Pathologist 17 Clear cell RCC Typical

Grade 4 with rhabdoid features

Pathologist 18 Other Not typical

??

Pathologist 19 Clear cell RCC Not typical

Rhabdoid differentiation present

Pathologist 20 Clear cell RCC Typical

Clear cell RCC with rhabdoid differentiation.



Case description (by case creator):

Clear cell renal cell carcinoma with rhabdoid differentiation