148027 | Bladder Flat Lesions

Case ID: 381

Publication date: 14 Apr, 2026

Consensus grade: Carcinoma in situ (CIS)

Show diagnosis by expert panel members

User	Diagnosis	Difficulty	Comment
Pathologist 1	Carcinoma in situ (CIS)	Typical
Pathologist 2	Carcinoma in situ (CIS)	Typical
Pathologist 3	Atypia/dysplasia	Borderline higher
Pathologist 4	Carcinoma in situ (CIS)	Typical
Pathologist 5	Carcinoma in situ (CIS)	Typical
Pathologist 6	Carcinoma in situ (CIS)	Typical
Pathologist 7	Carcinoma in situ (CIS)	Typical
Pathologist 8	Carcinoma in situ (CIS)	Typical
Pathologist 9	Carcinoma in situ (CIS)	Typical
Pathologist 10	Carcinoma in situ (CIS)	Typical
Pathologist 11	Carcinoma in situ (CIS)	Typical
Pathologist 12	Carcinoma in situ (CIS)	Typical
Pathologist 13	Carcinoma in situ (CIS)	Typical
Pathologist 14	Carcinoma in situ (CIS)	Typical
Pathologist 15	Carcinoma in situ (CIS)	Typical	No specific comment.
Pathologist 16	Carcinoma in situ (CIS)	Borderline lower	would use IHCH to verify, could also be reactive
Pathologist 17	Carcinoma in situ (CIS)	Typical
Pathologist 18	Carcinoma in situ (CIS)	Typical
Pathologist 19	Carcinoma in situ (CIS)	Typical

Case description (by case creator):

Lesion shows marked variation in nuclear size, shape and chromatin. Architecturally, cells appear irregularly clustered and the epithelium is disorganized.

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